Integration of Ligand-Based Drug Screening with Structure-Based Drug Screening by Combining Maximum Volume Overlapping Score with Ligand Doscking

Ligand-based and structure-based drug screening methods were integrated for in silico drug development by combining the maximum-volume overlap (MVO) method with a protein-compound docking program. The MVO method is used to select reliable docking poses by calculating volume overlaps between the dock...

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Detalles Bibliográficos
Autores principales: Fukunishi, Yoshifumi, Nakamura, Haruki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3816669/
https://www.ncbi.nlm.nih.gov/pubmed/24281339
http://dx.doi.org/10.3390/ph5121332

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3816669/
https://www.ncbi.nlm.nih.gov/pubmed/24281339
http://dx.doi.org/10.3390/ph5121332

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