Expression of Mesenchymal and α-Cell Phenotypic Markers in Islet β-Cells in Recently Diagnosed Diabetes

OBJECTIVE: Relative contributions of reversible β-cell dysfunction and true decrease in β-cell mass in type 2 diabetes remain unclear. Definitive rodent lineage-tracing studies have identified β-cell dedifferentiation and subsequent reprogramming to α-cell fate as a novel mechanism underlying β-cell...

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Detalles Bibliográficos
Autores principales: White, Michael G., Marshall, Helen L., Rigby, Rebecca, Huang, Guo Cai, Amer, Aimen, Booth, Trevor, White, Steve, Shaw, James A.M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Diabetes Association 2013
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3816907/
https://www.ncbi.nlm.nih.gov/pubmed/24062329
http://dx.doi.org/10.2337/dc13-0705

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