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IRS1 Genotype Modulates Metabolic Syndrome Reversion in Response to 2-Year Weight-Loss Diet Intervention: The POUNDS LOST trial

OBJECTIVE: Genetic variants near IRS1 are associated with features of the metabolic syndrome (MetS). We examined whether genetic variants near IRS1 might modulate the effects of diets varying in fat content on the MetS status in a 2-year weight-loss trial. RESEARCH DESIGN AND METHODS: Two variants n...

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Detalles Bibliográficos
Autores principales: Qi, Qibin, Xu, Min, Wu, Hongyu, Liang, Liming, Champagne, Catherine M., Bray, George A., Sacks, Frank M., Qi, Lu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Diabetes Association 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3816909/
https://www.ncbi.nlm.nih.gov/pubmed/24009303
http://dx.doi.org/10.2337/dc13-0018