Biodistribution of newly synthesized PHEA-based polymer-coated SPION in Sprague Dawley rats as magnetic resonance contrast agent

OBJECTIVES: The purpose of this study was to observe the pharmacokinetic behavior of newly synthesized biocompatible polymers based on polyhydroxyethylaspartamide (PHEA) to be used to coat an iron oxide core to make superparamagnetic iron oxide nanoparticles (SPION). MATERIALS AND METHODS: The isoto...

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Detalles Bibliográficos
Autores principales: Park, Junsung, Cho, Wonkyung, Park, Hee Jun, Cha, Kwang-Ho, Ha, Dae-Chul, Choi, Youn-Woong, Lee, Ha-Young, Cho, Sun-Hang, Hwang, Sung-Joo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2013
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3817023/
https://www.ncbi.nlm.nih.gov/pubmed/24204138
http://dx.doi.org/10.2147/IJN.S51684

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