GTP Hydrolysis of TC10 Promotes Neurite Outgrowth through Exocytic Fusion of Rab11- and L1-Containing Vesicles by Releasing Exocyst Component Exo70

The use of exocytosis for membrane expansion at nerve growth cones is critical for neurite outgrowth. TC10 is a Rho family GTPase that is essential for specific types of vesicular trafficking to the plasma membrane. Recent studies have shown that TC10 and its effector Exo70, a component of the exocy...

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Detalles Bibliográficos
Autores principales: Fujita, Akane, Koinuma, Shingo, Yasuda, Sayaka, Nagai, Hiroyuki, Kamiguchi, Hiroyuki, Wada, Naoyuki, Nakamura, Takeshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3817099/
https://www.ncbi.nlm.nih.gov/pubmed/24223996
http://dx.doi.org/10.1371/journal.pone.0079689

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