Tumor Stiffness Is Unrelated to Myosin Light Chain Phosphorylation in Cancer Cells

Many tumors are stiffer than their surrounding tissue. This increase in stiffness has been attributed, in part, to a Rho-dependent elevation of myosin II light chain phosphorylation. To characterize this mechanism further, we studied myosin light chain kinase (MLCK), the main enzyme that phosphoryla...

Descripción completa

Detalles Bibliográficos
Autores principales: Yu, Hui-Jun, Serebryannyy, Leonid A., Fry, Madeline, Greene, Madelyne, Chernaya, Olga, Hu, Wen-Yang, Chew, Teng-Leong, Mahmud, Nadim, Kadkol, Shrihari S., Glover, Sarah, Prins, Gail, Strakova, Zuzana, de Lanerolle, Primal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3817105/
https://www.ncbi.nlm.nih.gov/pubmed/24224004
http://dx.doi.org/10.1371/journal.pone.0079776

Ejemplares similares

Ejemplares similares