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Solution and Crystallographic Structures of the Central Region of the Phosphoprotein from Human Metapneumovirus

Human metapneumovirus (HMPV) of the family Paramyxoviridae is a major cause of respiratory illness worldwide. Phosphoproteins (P) from Paramyxoviridae are essential co-factors of the viral RNA polymerase that form tetramers and possess long intrinsically disordered regions (IDRs). We located the cen...

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Detalles Bibliográficos
Autores principales: Leyrat, Cedric, Renner, Max, Harlos, Karl, Grimes, Jonathan M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3817118/
https://www.ncbi.nlm.nih.gov/pubmed/24224051
http://dx.doi.org/10.1371/journal.pone.0080371