Chemokine Receptors CCR6 and CXCR3 Are Necessary for CD4(+) T Cell Mediated Ocular Surface Disease in Experimental Dry Eye Disease

CD4(+) T cells are essential to pathogenesis of ocular surface disease in dry eye. Two subtypes of CD4(+) T cells, Th1 and Th17 cells, function concurrently in dry eye to mediate disease. This occurs in spite of the cross-regulation of IFN-γ and IL-17A, the prototypical cytokines Th1 and Th17 cells,...

Descripción completa

Detalles Bibliográficos
Autores principales: Coursey, Terry G., Gandhi, Niral B., Volpe, Eugene A., Pflugfelder, Stephen C., de Paiva, Cintia S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3817213/
https://www.ncbi.nlm.nih.gov/pubmed/24223818
http://dx.doi.org/10.1371/journal.pone.0078508

Ejemplares similares

Ejemplares similares