The Role of Individual Domains and the Significance of Shedding of ATP6AP2/(pro)renin Receptor in Vacuolar H(+)-ATPase Biogenesis

The ATPase 6 accessory protein 2 (ATP6AP2)/(pro)renin receptor (PRR) is essential for the biogenesis of active vacuolar H(+)-ATPase (V-ATPase). Genetic deletion of ATP6AP2/PRR causes V-ATPase dysfunction and compromises vesicular acidification. Here, we characterized the domains of ATP6AP2/PRR invol...

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Detalles Bibliográficos
Autores principales: Kinouchi, Kenichiro, Ichihara, Atsuhiro, Sano, Motoaki, Sun-Wada, Ge-Hong, Wada, Yoh, Ochi, Hiroki, Fukuda, Toru, Bokuda, Kanako, Kurosawa, Hideaki, Yoshida, Naohiro, Takeda, Shu, Fukuda, Keiichi, Itoh, Hiroshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3817224/
https://www.ncbi.nlm.nih.gov/pubmed/24223829
http://dx.doi.org/10.1371/journal.pone.0078603

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