Cargando…

Do type 1 receptor tyrosine kinases inform treatment choice? A prospectively planned analysis of the TEAM trial

BACKGROUND: Epidermal growth factor receptors contribute to breast cancer relapse during endocrine therapy. Substitution of aromatase inhibitors (AIs) may improve outcomes in HER-positive cancers. METHODS: Tissue microarrays were constructed. Quantitative analysis of HER1, HER2, and HER3 was perform...

Descripción completa

Detalles Bibliográficos
Autores principales:	Bartlett, J M S, Brookes, C L, Piper, T, van de Velde, C J H, Stocken, D, Lyttle, N, Hasenburg, A, Quintayo, M A, Kieback, D G, Putter, H, Markopoulos, C, Kranenbarg, E M-K, Mallon, E A, Dirix, L Y, Seynaeve, C, Rea, D W
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2013
Materias:	Molecular Diagnostics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3817340/ https://www.ncbi.nlm.nih.gov/pubmed/24091623 http://dx.doi.org/10.1038/bjc.2013.609

Ejemplares similares

Molecular stratification of early breast cancer identifies drug targets to drive stratified medicine
por: Bayani, Jane, et al.
Publicado: (2017)

Time dependence of biomarkers: non-proportional effects of immunohistochemical panels predicting relapse risk in early breast cancer
por: Stephen, J, et al.
Publicado: (2014)

Comparative survival analysis of multiparametric tests—when molecular tests disagree—A TEAM Pathology study
por: Bartlett, John M. S., et al.
Publicado: (2021)

Pathway-based subnetworks enable cross-disease biomarker discovery
por: Haider, Syed, et al.
Publicado: (2018)

Epigenetic status of LINE-1 predicts clinical outcome in early-stage rectal cancer
por: Benard, A, et al.
Publicado: (2013)

Elevated serum matrix metalloproteinase 9 (MMP-9) concentration predicts the presence of colorectal neoplasia in symptomatic patients
por: Hurst, N G, et al.
Publicado: (2007)

PTK (protein tyrosine kinase)-6 and HER2 and 4, but not HER1 and 3 predict long-term survival in breast carcinomas
por: Aubele, M, et al.
Publicado: (2007)

Can mid-regional pro-adrenomedullin (MR-proADM) increase the prognostic accuracy of NEWS in predicting deterioration in patients admitted to hospital with mild to moderately severe illness? A prospective single-centre observational study
por: Graziadio, Sara, et al.
Publicado: (2018)

Prognostic value of protein tyrosine kinase 6 (PTK6) for long-term survival of breast cancer patients
por: Aubele, M, et al.
Publicado: (2008)

Clinical prognostic value of combined analysis of Aldh1, Survivin, and EpCAM expression in colorectal cancer
por: Goossens-Beumer, I J, et al.
Publicado: (2014)

Prognostic significance of chromosome 3 alterations determined by microsatellite analysis in uveal melanoma: a long-term follow-up study
por: Thomas, S, et al.
Publicado: (2012)

Early diagnosis of bladder cancer through the detection of urinary tyrosine-phosphorylated proteins
por: Khadjavi, A, et al.
Publicado: (2015)

Specific induction of pp125 focal adhesion kinase in human breast cancer
por: Watermann, D O, et al.
Publicado: (2005)

Comparison of Visual and automated assessment of Ki-67 proliferative activity and their impact on outcome in primary operable invasive ductal breast cancer
por: Mohammed, Z M A, et al.
Publicado: (2012)

Validation study of the prognostic value of cyclin-dependent kinase (CDK)-based risk in Caucasian breast cancer patients
por: van Nes, J G H, et al.
Publicado: (2009)

The expression of Axl receptor tyrosine kinase influences the tumour phenotype and clinical outcome of patients with malignant pleural mesothelioma
por: Pinato, D J, et al.
Publicado: (2013)

Ron tyrosine kinase receptor synergises with EGFR to confer adverse features in head and neck squamous cell carcinoma
por: Keller, J, et al.
Publicado: (2013)

Diagnostic and mechanistic implications of serum free light chains, albumin and alpha-fetoprotein in hepatocellular carcinoma
por: Teng, M, et al.
Publicado: (2014)

Serum matrix metalloproteinase 9 and colorectal neoplasia: a community-based evaluation of a potential diagnostic test
por: Wilson, S, et al.
Publicado: (2012)

Expression and prognostic impact of the protein tyrosine phosphatases PRL-1, PRL-2, and PRL-3 in breast cancer
por: Radke, I, et al.
Publicado: (2006)

Hypoxia-regulated carbonic anhydrase IX expression is associated with poor survival in patients with invasive breast cancer
por: Hussain, S A, et al.
Publicado: (2007)

Issues on fit-for-purpose validation of a panel of ELISAs for application as biomarkers in clinical trials of anti-Angiogenic drugs
por: Brookes, K, et al.
Publicado: (2010)

Assessment of DNA methylation status in early stages of breast cancer development
por: van Hoesel, A Q, et al.
Publicado: (2013)

Levels of circulating CD45(dim)CD34(+)VEGFR2(+) progenitor cells correlate with outcome in metastatic renal cell carcinoma patients treated with tyrosine kinase inhibitors
por: Farace, F, et al.
Publicado: (2011)

Tumour-infiltrating lymphocytes predict for outcome in HPV-positive oropharyngeal cancer
por: Ward, M J, et al.
Publicado: (2014)

TNF-receptor-1 adaptor protein FAN mediates TNF-induced B16 melanoma motility and invasion
por: Boecke, A, et al.
Publicado: (2013)

Immunological subtypes in breast cancer are prognostic for invasive ductal but not for invasive lobular breast carcinoma
por: Engels, C C, et al.
Publicado: (2014)

Real-time RT–PCR detection of disseminated tumour cells in bone marrow has superior prognostic significance in comparison with circulating tumour cells in patients with breast cancer
por: Benoy, I H, et al.
Publicado: (2006)

Detection and prognostic significance of circulating tumour cells in patients with metastatic breast cancer according to immunohistochemical subtypes
por: Peeters, D J E, et al.
Publicado: (2014)

Subarachnoid haemorrhage guidelines and clinical practice: a cross-sectional study of emergency department consultants' and neurospecialists' views and risk tolerances
por: Lansley, J, et al.
Publicado: (2016)

Expression of the proteolysis-inducing factor core peptide mRNA is upregulated in both tumour and adjacent normal tissue in gastro-oesophageal malignancy
por: Deans, D A C, et al.
Publicado: (2006)

The prognostic and predictive value of Tregs and tumor immune subtypes in postmenopausal, hormone receptor-positive breast cancer patients treated with adjuvant endocrine therapy: a Dutch TEAM study analysis
por: Engels, C. C., et al.
Publicado: (2015)

Circulating tumour cells in the central and the peripheral venous compartment in patients with metastatic breast cancer
por: Peeters, D J E, et al.
Publicado: (2011)

Diagnostic accuracy of history taking, physical examination and imaging for non-chronic finger, hand and wrist ligament and tendon injuries: a systematic review update
por: Krastman, Patrick, et al.
Publicado: (2020)

Semiautomated isolation and molecular characterisation of single or highly purified tumour cells from CellSearch enriched blood samples using dielectrophoretic cell sorting
por: Peeters, D J E, et al.
Publicado: (2013)

Tissue microarrays characterise the clinical significance of a VEGF-A protein expression signature in gastrointestinal stromal tumours
por: Salto-Tellez, M, et al.
Publicado: (2007)

Co-expression of KLK6 and KLK10 as prognostic factors for survival in pancreatic ductal adenocarcinoma
por: Rückert, F, et al.
Publicado: (2008)

Mutations within the tyrosine kinase domain of EGFR gene specifically occur in lung adenocarcinoma patients with a low exposure of tobacco smoking
por: Sugio, K, et al.
Publicado: (2006)

Increased expression of phosphorylated forms of RNA-dependent protein kinase and eukaryotic initiation factor 2α may signal skeletal muscle atrophy in weight-losing cancer patients
por: Eley, H L, et al.
Publicado: (2008)

Matrix metalloproteinase-2 is a consistent prognostic factor in gastric cancer
por: Kubben, F J G M, et al.
Publicado: (2006)

Cannot write session to /tmp/vufind_sessions/sess_cj0ho2jbtm9bntb2nqlloksej3