Cargando…
A competitive protein interaction network buffers Oct4-mediated differentiation to promote pluripotency in embryonic stem cells
Pluripotency in embryonic stem cells is maintained through the activity of a small set of transcription factors centred around Oct4 and Nanog, which control the expression of ‘self-renewal’ and ‘differentiation’ genes. Here, we combine single-cell quantitative immunofluorescence microscopy and gene...
| Autores principales: | , , , , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
European Molecular Biology Organization
2013
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3817399/ https://www.ncbi.nlm.nih.gov/pubmed/24104477 http://dx.doi.org/10.1038/msb.2013.49 |