Production of Sry knockout mouse using TALEN via oocyte injection

Recently developed transcription activator-like effector nuclease (TALEN) technology has enabled the creation of knockout mice, even for genes on the Y chromosome. In this study, we generated a knockout mouse for Sry, a sex-determining gene on the Y chromosome, using microinjection of TALEN RNA into...

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Detalles Bibliográficos
Autores principales: Kato, Tomoko, Miyata, Kohei, Sonobe, Miku, Yamashita, Satoshi, Tamano, Moe, Miura, Kento, Kanai, Yoshiakira, Miyamoto, Shingo, Sakuma, Tetsushi, Yamamoto, Takashi, Inui, Masafumi, Kikusui, Takefumi, Asahara, Hiroshi, Takada, Shuji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3817445/
https://www.ncbi.nlm.nih.gov/pubmed/24190364
http://dx.doi.org/10.1038/srep03136

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3817445/
https://www.ncbi.nlm.nih.gov/pubmed/24190364
http://dx.doi.org/10.1038/srep03136

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