Non-cross-linked polystyrene-supported 2-imidazolidinone chiral auxiliary: synthesis and application in asymmetric alkylation reactions

Asymmetric alkylation reactions using non-cross-linked polystyrene (NCPS)-supported 2-imidazolidinone chiral auxiliaries were successfully investigated with excellent diastereocontrol (>99% de). The recovery and the recycling of this soluble polymer-supported chiral auxiliary were achieved in ord...

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Autores principales: Nguyen, Quynh Pham Bao, Kim, Taek Hyeon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Beilstein-Institut 2013
Materias:
Full Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3817508/
https://www.ncbi.nlm.nih.gov/pubmed/24204423
http://dx.doi.org/10.3762/bjoc.9.248
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author Nguyen, Quynh Pham Bao
Kim, Taek Hyeon
author_facet Nguyen, Quynh Pham Bao
Kim, Taek Hyeon
author_sort Nguyen, Quynh Pham Bao
collection PubMed
description Asymmetric alkylation reactions using non-cross-linked polystyrene (NCPS)-supported 2-imidazolidinone chiral auxiliaries were successfully investigated with excellent diastereocontrol (>99% de). The recovery and the recycling of this soluble polymer-supported chiral auxiliary were achieved in order to produce highly optical pure carboxylic acids.
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spelling pubmed-38175082013-11-07 Non-cross-linked polystyrene-supported 2-imidazolidinone chiral auxiliary: synthesis and application in asymmetric alkylation reactions Nguyen, Quynh Pham Bao Kim, Taek Hyeon Beilstein J Org Chem Full Research Paper Asymmetric alkylation reactions using non-cross-linked polystyrene (NCPS)-supported 2-imidazolidinone chiral auxiliaries were successfully investigated with excellent diastereocontrol (>99% de). The recovery and the recycling of this soluble polymer-supported chiral auxiliary were achieved in order to produce highly optical pure carboxylic acids. Beilstein-Institut 2013-10-15 /pmc/articles/PMC3817508/ /pubmed/24204423 http://dx.doi.org/10.3762/bjoc.9.248 Text en Copyright © 2013, Nguyen and Kim https://creativecommons.org/licenses/by/2.0https://www.beilstein-journals.org/bjoc/termsThis is an Open Access article under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. The license is subject to the Beilstein Journal of Organic Chemistry terms and conditions: (https://www.beilstein-journals.org/bjoc/terms)
spellingShingle Full Research Paper
Nguyen, Quynh Pham Bao
Kim, Taek Hyeon
Non-cross-linked polystyrene-supported 2-imidazolidinone chiral auxiliary: synthesis and application in asymmetric alkylation reactions
title Non-cross-linked polystyrene-supported 2-imidazolidinone chiral auxiliary: synthesis and application in asymmetric alkylation reactions
title_full Non-cross-linked polystyrene-supported 2-imidazolidinone chiral auxiliary: synthesis and application in asymmetric alkylation reactions
title_fullStr Non-cross-linked polystyrene-supported 2-imidazolidinone chiral auxiliary: synthesis and application in asymmetric alkylation reactions
title_full_unstemmed Non-cross-linked polystyrene-supported 2-imidazolidinone chiral auxiliary: synthesis and application in asymmetric alkylation reactions
title_short Non-cross-linked polystyrene-supported 2-imidazolidinone chiral auxiliary: synthesis and application in asymmetric alkylation reactions
title_sort non-cross-linked polystyrene-supported 2-imidazolidinone chiral auxiliary: synthesis and application in asymmetric alkylation reactions
topic Full Research Paper
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3817508/
https://www.ncbi.nlm.nih.gov/pubmed/24204423
http://dx.doi.org/10.3762/bjoc.9.248
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