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Flow synthesis of a versatile fructosamine mimic and quenching studies of a fructose transport probe

We describe the synthesis of 1-amino-2,5-anhydro-D-mannose (“mannitolamine”), a key intermediate to the 7-nitro-1,2,3-benzadiazole conjugate (NBDM), using commercially available fluidic devices to increase the throughput. The approach is the first example of a flow-based Tiffeneau–Demjanov rearrange...

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Detalles Bibliográficos
Autores principales: Plutschack, Matthew B, McQuade, D Tyler, Valenti, Giulio, Seeberger, Peter H
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Beilstein-Institut 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3817519/
https://www.ncbi.nlm.nih.gov/pubmed/24204413
http://dx.doi.org/10.3762/bjoc.9.238

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