Synthesis of enantiomerically pure (2S,3S)-5,5,5-trifluoroisoleucine and (2R,3S)-5,5,5-trifluoro-allo-isoleucine

A practical route for the stereoselective synthesis of (2S,3S)-5,5,5-trifluoroisoleucine (L-5-F(3)Ile) and (2R,3S)-5,5,5-trifluoro-allo-isoleucine (D-5-F(3)-allo-Ile) was developed. The hydrophobicity of L-5-F(3)Ile was examined and it was incorporated into a model peptide via solid phase peptide sy...

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Detalles Bibliográficos
Autores principales: Erdbrink, Holger, Nyakatura, Elisabeth K, Huhmann, Susanne, Gerling, Ulla I M, Lentz, Dieter, Koksch, Beate, Czekelius, Constantin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Beilstein-Institut 2013
Materias:
Full Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3817528/
https://www.ncbi.nlm.nih.gov/pubmed/24204411
http://dx.doi.org/10.3762/bjoc.9.236

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3817528/
https://www.ncbi.nlm.nih.gov/pubmed/24204411
http://dx.doi.org/10.3762/bjoc.9.236

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