Activating Group Recycling in Action: A Rhodium-Catalyzed Carbothiolation Route to Substituted Isoquinolines

[Image: see text] A new rhodium(I) catalyst allows practical and efficient alkyne carbothiolation reactions to be achieved on synthetically useful ketone-bearing aryl methyl sulfides. The carbothiolation adducts, featuring a ‘recycled methyl sulfide’ activating group, are convenient precursors to hi...

Descripción completa

Detalles Bibliográficos
Autores principales: Arambasic, Milan, Hooper, Joel F., Willis, Michael C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2013
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3817538/
https://www.ncbi.nlm.nih.gov/pubmed/24083625
http://dx.doi.org/10.1021/ol402650q
_version_ 1782478090295836672
author Arambasic, Milan
Hooper, Joel F.
Willis, Michael C.
author_facet Arambasic, Milan
Hooper, Joel F.
Willis, Michael C.
author_sort Arambasic, Milan
collection PubMed
description [Image: see text] A new rhodium(I) catalyst allows practical and efficient alkyne carbothiolation reactions to be achieved on synthetically useful ketone-bearing aryl methyl sulfides. The carbothiolation adducts, featuring a ‘recycled methyl sulfide’ activating group, are convenient precursors to highly substituted isoquinolines.
format Online
Article
Text
id pubmed-3817538
institution National Center for Biotechnology Information
language English
publishDate 2013
publisher American Chemical Society
record_format MEDLINE/PubMed
spelling pubmed-38175382013-11-05 Activating Group Recycling in Action: A Rhodium-Catalyzed Carbothiolation Route to Substituted Isoquinolines Arambasic, Milan Hooper, Joel F. Willis, Michael C. Org Lett [Image: see text] A new rhodium(I) catalyst allows practical and efficient alkyne carbothiolation reactions to be achieved on synthetically useful ketone-bearing aryl methyl sulfides. The carbothiolation adducts, featuring a ‘recycled methyl sulfide’ activating group, are convenient precursors to highly substituted isoquinolines. American Chemical Society 2013-10-01 2013-10-18 /pmc/articles/PMC3817538/ /pubmed/24083625 http://dx.doi.org/10.1021/ol402650q Text en Copyright © 2013 American Chemical Society Terms of Use CC-BY (http://pubs.acs.org/page/policy/authorchoice_ccby_termsofuse.html)
spellingShingle Arambasic, Milan
Hooper, Joel F.
Willis, Michael C.
Activating Group Recycling in Action: A Rhodium-Catalyzed Carbothiolation Route to Substituted Isoquinolines
title Activating Group Recycling in Action: A Rhodium-Catalyzed Carbothiolation Route to Substituted Isoquinolines
title_full Activating Group Recycling in Action: A Rhodium-Catalyzed Carbothiolation Route to Substituted Isoquinolines
title_fullStr Activating Group Recycling in Action: A Rhodium-Catalyzed Carbothiolation Route to Substituted Isoquinolines
title_full_unstemmed Activating Group Recycling in Action: A Rhodium-Catalyzed Carbothiolation Route to Substituted Isoquinolines
title_short Activating Group Recycling in Action: A Rhodium-Catalyzed Carbothiolation Route to Substituted Isoquinolines
title_sort activating group recycling in action: a rhodium-catalyzed carbothiolation route to substituted isoquinolines
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3817538/
https://www.ncbi.nlm.nih.gov/pubmed/24083625
http://dx.doi.org/10.1021/ol402650q
work_keys_str_mv AT arambasicmilan activatinggrouprecyclinginactionarhodiumcatalyzedcarbothiolationroutetosubstitutedisoquinolines
AT hooperjoelf activatinggrouprecyclinginactionarhodiumcatalyzedcarbothiolationroutetosubstitutedisoquinolines
AT willismichaelc activatinggrouprecyclinginactionarhodiumcatalyzedcarbothiolationroutetosubstitutedisoquinolines

Ejemplares similares