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Mitochondrial H(2)O(2) as an enable signal for triggering autophosphorylation of insulin receptor in neurons

BACKGROUND: Insulin receptors are widely distributed in the brain, where they play roles in synaptic function, memory formation, and neuroprotection. Autophosphorylation of the receptor in response to insulin stimulation is a critical step in receptor activation. In neurons, insulin stimulation lead...

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Detalles Bibliográficos
Autores principales:	Persiyantseva, Nadezhda A, Storozhevykh, Tatiana P, Senilova, Yana E, Gorbacheva, Lubov R, Pinelis, Vsevolod G, Pomytkin, Igor A
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3817577/ https://www.ncbi.nlm.nih.gov/pubmed/24094269 http://dx.doi.org/10.1186/1750-2187-8-11

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