Cargando…

Glibenclamide for the Treatment of Acute CNS Injury

First introduced into clinical practice in 1969, glibenclamide (US adopted name, glyburide) is known best for its use in the treatment of diabetes mellitus type 2, where it is used to promote the release of insulin by blocking pancreatic K(ATP) [sulfonylurea receptor 1 (Sur1)-Kir6.2] channels. Durin...

Descripción completa

Detalles Bibliográficos
Autores principales:	Kurland, David B., Tosun, Cigdem, Pampori, Adam, Karimy, Jason K., Caffes, Nicholas M., Gerzanich, Volodymyr, Simard, J. Marc
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2013
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3817601/ https://www.ncbi.nlm.nih.gov/pubmed/24275850 http://dx.doi.org/10.3390/ph6101287

Ejemplares similares

Glibenclamide for the Treatment of Ischemic and Hemorrhagic Stroke
por: Caffes, Nicholas, et al.
Publicado: (2015)

The Protective Effect of Glibenclamide in a Model of Hemorrhagic Encephalopathy of Prematurity
por: Tosun, Cigdem, et al.
Publicado: (2013)

Glibenclamide—10-h Treatment Window in a Clinically Relevant Model of Stroke
por: Simard, J. Marc, et al.
Publicado: (2012)

Changes in Diffusion Kurtosis Imaging and Magnetic Resonance Spectroscopy in a Direct Cranial Blast Traumatic Brain Injury (dc-bTBI) Model
por: Zhuo, Jiachen, et al.
Publicado: (2015)

MRI evidence that glibenclamide reduces acute lesion expansion in a rat model of spinal cord injury
por: Simard, JM, et al.
Publicado: (2013)

The Sur1-Trpm4 channel regulates NOS2 transcription in TLR4-activated microglia
por: Kurland, David B., et al.
Publicado: (2016)

Heparin Reduces Neuroinflammation and Transsynaptic Neuronal Apoptosis in a Model of Subarachnoid Hemorrhage
por: Simard, J. Marc, et al.
Publicado: (2012)

Precision Effects of Glibenclamide on MRI Endophenotypes in Clinically Relevant Murine Traumatic Brain Injury
por: Zusman, Benjamin E., et al.
Publicado: (2022)

Angiogenesis induced by prenatal ischemia predisposes to periventricular hemorrhage during postnatal mechanical ventilation
por: Tosun, Cigdem, et al.
Publicado: (2015)

Salutary effects of glibenclamide during the chronic phase of murine experimental autoimmune encephalomyelitis
por: Gerzanich, Volodymyr, et al.
Publicado: (2017)

Sulfonylurea Receptor 1 Expression in Human Cerebral Infarcts
por: Mehta, Rupal I., et al.
Publicado: (2013)

Sulfonylurea receptor 1 in central nervous system injury: a focused review
por: Simard, J Marc, et al.
Publicado: (2012)

TRPM4 and the Emperor
por: Simard, J. Marc, et al.
Publicado: (2017)

Inducible nitric oxide synthase (NOS-2) in subarachnoid hemorrhage: Regulatory mechanisms and therapeutic implications
por: Iqbal, Sana, et al.
Publicado: (2016)

Traumatic brain injury alters dendritic cell differentiation and distribution in lymphoid and non-lymphoid organs
por: Tsymbalyuk, Orest, et al.
Publicado: (2022)

Canagliflozin, an Inhibitor of the Na(+)-Coupled D-Glucose Cotransporter, SGLT2, Inhibits Astrocyte Swelling and Brain Swelling in Cerebral Ischemia
por: Shim, Bosung, et al.
Publicado: (2023)

Role of Sulfonylurea Receptor 1 and Glibenclamide in Traumatic Brain Injury: A Review of the Evidence
por: Jha, Ruchira M., et al.
Publicado: (2020)

Transient receptor potential melastatin 4 and cell death
por: Simard, J. Marc, et al.
Publicado: (2012)

Pharmacological induced target temperature management after cardiac arrest: the capsaicinoids
por: Simard, J. Marc, et al.
Publicado: (2017)

Cerebral microbleeds in a neonatal rat model
por: Carusillo Theriault, Brianna, et al.
Publicado: (2017)

Correction: Cerebral microbleeds in a neonatal rat model
por: Theriault, Brianna C., et al.
Publicado: (2018)

Molecular pathophysiology of cerebral edema
por: Stokum, Jesse A, et al.
Publicado: (2015)

A Protective Role of Glibenclamide in Inflammation-Associated Injury
por: Zhang, Gensheng, et al.
Publicado: (2017)

Glibenclamide for Brain Contusions: Contextualizing a Promising Clinical Trial Design that Leverages an Imaging-Based TBI Endotype
por: Jha, Ruchira M., et al.
Publicado: (2023)

A Direct Comparison of Three Clinically Relevant Treatments in a Rat Model of Cervical Spinal Cord Injury
por: Hosier, Hillary, et al.
Publicado: (2015)

Hypoxanthine is a pharmacodynamic marker of ischemic brain edema modified by glibenclamide
por: Irvine, Hannah J., et al.
Publicado: (2022)

Methemoglobin Is an Endogenous Toll-Like Receptor 4 Ligand—Relevance to Subarachnoid Hemorrhage
por: Kwon, Min Seong, et al.
Publicado: (2015)

Glibenclamide attenuates myocardial injury by lipopolysaccharides in streptozotocin-induced diabetic mice
por: Cai, Jian, et al.
Publicado: (2014)

Glibenclamide Alleviates LPS-Induced Acute Lung Injury through NLRP3 Inflammasome Signaling Pathway
por: Yang, Jie, et al.
Publicado: (2022)

Interaction of Herbs and Glibenclamide: A Review
por: Rai, Amita, et al.
Publicado: (2012)

Glibenclamide Prevents Diabetes in NOD Mice
por: Lamprianou, Smaragda, et al.
Publicado: (2016)

The Sulfonylurea Receptor 1 (Sur1)-Transient Receptor Potential Melastatin 4 (Trpm4) Channel
por: Woo, Seung Kyoon, et al.
Publicado: (2013)

SUR1-TRPM4 channel activation and phasic secretion of MMP-9 induced by tPA in brain endothelial cells
por: Gerzanich, Volodymyr, et al.
Publicado: (2018)

Direct versus indirect actions of ghrelin on hypothalamic NPY neurons
por: Hashiguchi, Hiroshi, et al.
Publicado: (2017)

BIIB093 (intravenous glibenclamide) for the prevention of severe cerebral edema
por: Griepp, Daniel W., et al.
Publicado: (2021)

Chronic pain after blast-induced traumatic brain injury in awake rats
por: Uddin, Olivia, et al.
Publicado: (2019)

A Direct Comparison of Physical Versus Dihydrocapsaicin-Induced Hypothermia in a Rat Model of Traumatic Spinal Cord Injury
por: Sarkar, Amrita, et al.
Publicado: (2022)

Mucoadhesive buccal films of glibenclamide: Development and evaluation
por: Muzib, Y Indira, et al.
Publicado: (2011)

Glibenclamide dose response in patients with septic shock
por: Morelli, A, et al.
Publicado: (2007)

Pharmacokinetic interaction of curcumin and glibenclamide in diabetic rats
por: Devi, P. R. Sakunthala, et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_8bq9emg5hreq1ikmulj7inqj5i