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Rationale and Means to Target Pro-Inflammatory Interleukin-8 (CXCL8) Signaling in Cancer

It is well established that chronic inflammation underpins the development of a number of human cancers, with pro-inflammatory signaling within the tumor microenvironment contributing to tumor progression and metastasis. CXCL8 is an ELR(+) pro-inflammatory CXC-chemokine which mediates its effects vi...

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Detalles Bibliográficos
Autores principales: Campbell, Laura M., Maxwell, Pamela J., Waugh, David J.J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3817732/
https://www.ncbi.nlm.nih.gov/pubmed/24276377
http://dx.doi.org/10.3390/ph6080929