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Rac function is crucial for cell migration but is not required for spreading and focal adhesion formation

Cell migration is commonly accompanied by protrusion of membrane ruffles and lamellipodia. In two-dimensional migration, protrusion of these thin sheets of cytoplasm is considered relevant to both exploration of new space and initiation of nascent adhesion to the substratum. Lamellipodium formation...

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Detalles Bibliográficos
Autores principales: Steffen, Anika, Ladwein, Markus, Dimchev, Georgi A., Hein, Anke, Schwenkmezger, Lisa, Arens, Stefan, Ladwein, Kathrin I., Margit Holleboom, J., Schur, Florian, Victor Small, J., Schwarz, Janett, Gerhard, Ralf, Faix, Jan, Stradal, Theresia E. B., Brakebusch, Cord, Rottner, Klemens
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3817791/
https://www.ncbi.nlm.nih.gov/pubmed/23902686
http://dx.doi.org/10.1242/jcs.118232