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Antimicrobial peptide β-defensin-1 expression is upregulated in Alzheimer’s brain

BACKGROUND: The human β-defensins (hBDs) are a highly conserved family of cationic antimicrobial and immunomodulatory peptides expressed primarily by epithelial cells in response to invasion by bacteria, fungi and some viruses. To date, the most studied members of this family of peptides are hBD-1,...

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Detalles Bibliográficos
Autores principales: Williams, Wesley M, Torres, Sandy, Siedlak, Sandra L, Castellani, Rudy J, Perry, George, Smith, Mark A, Zhu, Xiongwei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3817866/
https://www.ncbi.nlm.nih.gov/pubmed/24139179
http://dx.doi.org/10.1186/1742-2094-10-127