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Antimicrobial peptide β-defensin-1 expression is upregulated in Alzheimer’s brain
BACKGROUND: The human β-defensins (hBDs) are a highly conserved family of cationic antimicrobial and immunomodulatory peptides expressed primarily by epithelial cells in response to invasion by bacteria, fungi and some viruses. To date, the most studied members of this family of peptides are hBD-1,...
Autores principales: | Williams, Wesley M, Torres, Sandy, Siedlak, Sandra L, Castellani, Rudy J, Perry, George, Smith, Mark A, Zhu, Xiongwei |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3817866/ https://www.ncbi.nlm.nih.gov/pubmed/24139179 http://dx.doi.org/10.1186/1742-2094-10-127 |
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