Novel Disulfide Bond-Mediated Dimerization of the CARD Domain Was Revealed by the Crystal Structure of CARMA1 CARD

CARMA1, BCL10 and MALT1 form a large molecular complex known as the CARMA1 signalosome during lymphocyte activation. Lymphocyte activation via the CARMA1 signalosome is critical to immune response and linked to many immune diseases. Despite the important role of the CARMA1 signalosome during lymphoc...

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Detalles Bibliográficos
Autores principales: Jang, Tae-ho, Park, Jin Hee, Park, Hyun Ho
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3818214/
https://www.ncbi.nlm.nih.gov/pubmed/24224005
http://dx.doi.org/10.1371/journal.pone.0079778

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3818214/
https://www.ncbi.nlm.nih.gov/pubmed/24224005
http://dx.doi.org/10.1371/journal.pone.0079778

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