Cargando…
The Exosome Cofactor Rrp47 Is Critical for the Stability and Normal Expression of Its Associated Exoribonuclease Rrp6 in Saccharomyces cerevisiae
Rrp6 is a conserved catalytic subunit of the eukaryotic nuclear exosome ribonuclease complex that functions in the productive 3’ end maturation of stable RNAs, the degradation of transiently expressed noncoding transcripts and in discard pathways that eradicate the cell of incorrectly processed or a...
Autores principales: | Feigenbutz, Monika, Garland, William, Turner, Martin, Mitchell, Phil |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3818262/ https://www.ncbi.nlm.nih.gov/pubmed/24224060 http://dx.doi.org/10.1371/journal.pone.0080752 |
Ejemplares similares
-
Assembly of the Yeast Exoribonuclease Rrp6 with Its Associated Cofactor Rrp47 Occurs in the Nucleus and Is Critical for the Controlled Expression of Rrp47
por: Feigenbutz, Monika, et al.
Publicado: (2013) -
Rrp47 functions in RNA surveillance and stable RNA processing when divorced from the exoribonuclease and exosome-binding domains of Rrp6
por: Garland, William, et al.
Publicado: (2013) -
The PMC2NT domain of the catalytic exosome subunit Rrp6p provides the interface for binding with its cofactor Rrp47p, a nucleic acid-binding protein
por: Stead, Jonathan A., et al.
Publicado: (2007) -
Evidence for core exosome independent function of the nuclear exoribonuclease Rrp6p
por: Callahan, Kevin P., et al.
Publicado: (2008) -
The C-terminal Region of the Exosome-associated Protein Rrp47 Is Specifically Required for Box C/D Small Nucleolar RNA 3′-Maturation
por: Costello, Joe L., et al.
Publicado: (2011)