Intestinal DMBT1 Expression Is Modulated by Crohn’s Disease-Associated IL23R Variants and by a DMBT1 Variant Which Influences Binding of the Transcription Factors CREB1 and ATF-2

OBJECTIVES: DMBT is an antibacterial pattern recognition and scavenger receptor. In this study, we analyzed the role of DMBT1 single nucleotide polymorphisms (SNPs) regarding inflammatory bowel disease (IBD) susceptibility and examined their functional impact on transcription factor binding and down...

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Detalles Bibliográficos
Autores principales: Diegelmann, Julia, Czamara, Darina, Le Bras, Emmanuelle, Zimmermann, Eva, Olszak, Torsten, Bedynek, Andrea, Göke, Burkhard, Franke, Andre, Glas, Jürgen, Brand, Stephan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3818382/
https://www.ncbi.nlm.nih.gov/pubmed/24223725
http://dx.doi.org/10.1371/journal.pone.0077773

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3818382/
https://www.ncbi.nlm.nih.gov/pubmed/24223725
http://dx.doi.org/10.1371/journal.pone.0077773

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