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Engineering production of functional scFv antibody in E. coli by co-expressing the molecule chaperone Skp
Single-chain variable fragment (scFv) is a class of engineered antibodies generated by the fusion of the heavy (V(H)) and light chains (V(L)) of immunoglobulins through a short polypeptide linker. ScFv play a critical role in therapy and diagnosis of human diseases, and may in fact also be developed...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2013
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3818579/ https://www.ncbi.nlm.nih.gov/pubmed/24224158 http://dx.doi.org/10.3389/fcimb.2013.00072 |