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Microfluidic Preparation of Polymer-Nucleic Acid Nanocomplexes Improves Nonviral Gene Transfer

As the designs of polymer systems used to deliver nucleic acids continue to evolve, it is becoming increasingly apparent that the basic bulk manufacturing techniques of the past will be insufficient to produce polymer-nucleic acid nanocomplexes that possess the uniformity, stability, and potency req...

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Detalles Bibliográficos
Autores principales: Grigsby, Christopher L., Ho, Yi-Ping, Lin, Chao, Engbersen, Johan F. J., Leong, Kam W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3818651/
https://www.ncbi.nlm.nih.gov/pubmed/24193511
http://dx.doi.org/10.1038/srep03155