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Engineering Streptomyces coelicolor for heterologous expression of secondary metabolite gene clusters

We have constructed derivatives of Streptomyces coelicolor M145 as hosts for the heterologous expression of secondary metabolite gene clusters. To remove potentially competitive sinks of carbon and nitrogen, and to provide a host devoid of antibiotic activity, we deleted four endogenous secondary me...

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Detalles Bibliográficos
Autores principales:	Gomez‐Escribano, Juan Pablo, Bibb, Mervyn J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Blackwell Publishing Ltd 2011
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3818861/ https://www.ncbi.nlm.nih.gov/pubmed/21342466 http://dx.doi.org/10.1111/j.1751-7915.2010.00219.x

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