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Genome‐wide gene expression changes in an industrial clavulanic acid overproduction strain of Streptomyces clavuligerus

To increase production of the important pharmaceutical compound clavulanic acid, a β‐lactamase inhibitor, both random mutagenesis approaches and rational engineering of Streptomyces clavuligerus strains have been extensively applied. Here, for the first time, we compared genome‐wide gene expression...

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Detalles Bibliográficos
Autores principales:	Medema, Marnix H., Alam, Mohammad T., Heijne, Wilbert H. M., van den Berg, Marco A., Müller, Ulrike, Trefzer, Axel, Bovenberg, Roel A. L., Breitling, Rainer, Takano, Eriko
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Blackwell Publishing Ltd 2011
Materias:	Brief Report
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3818869/ https://www.ncbi.nlm.nih.gov/pubmed/21342474 http://dx.doi.org/10.1111/j.1751-7915.2010.00226.x

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