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Conditional testing of multiple variants associated with bone mineral density in the FLNB gene region suggests that they represent a single association signal

BACKGROUND: Low bone mineral density (BMD) is a primary risk factor for osteoporosis and is a highly heritable trait, but appears to be influenced by many genes. Genome-wide linkage studies have highlighted the chromosomal region 3p14-p22 as a quantitative trait locus for BMD (LOD 1.1 - 3.5). The FL...

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Detalles Bibliográficos
Autores principales:	Mullin, Benjamin H, Mamotte, Cyril, Prince, Richard L, Spector, Tim D, Dudbridge, Frank, Wilson, Scott G
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3818969/ https://www.ncbi.nlm.nih.gov/pubmed/24176111 http://dx.doi.org/10.1186/1471-2156-14-107

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