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Domain shuffling and module engineering of Listeria phage endolysins for enhanced lytic activity and binding affinity
Bacteriophage endolysins are peptidoglycan hydrolases employed by the virus to lyse the host at the end of its multiplication phase. They have found many uses in biotechnology; not only as antimicrobials, but also for the development of novel diagnostic tools for rapid detection of pathogenic bacter...
Autores principales: | Schmelcher, Mathias, Tchang, Vincent S., Loessner, Martin J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Blackwell Publishing Ltd
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3819014/ https://www.ncbi.nlm.nih.gov/pubmed/21535426 http://dx.doi.org/10.1111/j.1751-7915.2011.00263.x |
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