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Mifepristone Promotes Adiponectin Production and Improves Insulin Sensitivity in a Mouse Model of Diet-Induced-Obesity

The steroid receptor antagonist mifepristone is used as an anti-cancer agent, eliciting both cytostatic and cytotoxic effects on malignant cells. However, the metabolic effects of long-term treatment with mifepristone have remained unclear. The effects of mifepristone on insulin sensitivity and adip...

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Detalles Bibliográficos
Autores principales: Hashimoto, Takeshi, Igarashi, Junsuke, Hasan, Arif U., Ohmori, Koji, Kohno, Masakazu, Nagai, Yukiko, Yamashita, Tetsuo, Kosaka, Hiroaki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3819252/
https://www.ncbi.nlm.nih.gov/pubmed/24223187
http://dx.doi.org/10.1371/journal.pone.0079724