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Branched-Chain Amino Acids Enhance Premature Senescence through Mammalian Target of Rapamycin Complex I-Mediated Upregulation of p21 Protein

Branched-chain amino acids (BCAAs) have been applied as an oral supplementation to patients with liver cirrhosis. BCAAs not only improve nutritional status of patients but also decrease the incidence of liver cancer. Mammalian target of rapamycin (mTOR) links cellular metabolism with growth and prol...

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Detalles Bibliográficos
Autores principales:	Nakano, Masayuki, Nakashima, Akio, Nagano, Taiki, Ishikawa, Shintaro, Kikkawa, Ushio, Kamada, Shinji
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3819289/ https://www.ncbi.nlm.nih.gov/pubmed/24223226 http://dx.doi.org/10.1371/journal.pone.0080411

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