A Novel Chordoma Xenograft Allows In Vivo Drug Testing and Reveals the Importance of NF-κB Signaling in Chordoma Biology

Chordoma is a rare primary bone malignancy that arises in the skull base, spine and sacrum and originates from remnants of the notochord. These tumors are typically resistant to conventional chemotherapy, and to date there are no FDA-approved agents to treat chordoma. The lack of in vivo models of c...

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Detalles Bibliográficos
Autores principales: Trucco, Matteo M., Awad, Ola, Wilky, Breelyn A., Goldstein, Seth D., Huang, Ruili, Walker, Robert L., Shah, Preeti, Katuri, Varalakshmi, Gul, Naheed, Zhu, Yuelin J., McCarthy, Edward F., Paz-Priel, Ido, Meltzer, Paul S., Austin, Christopher P., Xia, Menghang, Loeb, David M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3819300/
https://www.ncbi.nlm.nih.gov/pubmed/24223206
http://dx.doi.org/10.1371/journal.pone.0079950

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