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Intratibial Injection of Human Multiple Myeloma Cells in NOD/SCID IL-2Rγ(Null) Mice Mimics Human Myeloma and Serves as a Valuable Tool for the Development of Anticancer Strategies
BACKGROUND: We systematically analyzed multiple myeloma (MM) cell lines and patient bone marrow cells for their engraftment capacity in immunodeficient mice and validated the response of the resulting xenografts to antimyeloma agents. DESIGN AND METHODS: Using flow cytometry and near infrared fluore...
Autores principales: | Schueler, Julia, Wider, Dagmar, Klingner, Kerstin, Siegers, Gabrielle M., May, Annette M., Wäsch, Ralph, Fiebig, Heinz-Herbert, Engelhardt, Monika |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3819303/ https://www.ncbi.nlm.nih.gov/pubmed/24223204 http://dx.doi.org/10.1371/journal.pone.0079939 |
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