Bone Marrow Deficiency of MCPIP1 Results in Severe Multi-Organ Inflammation but Diminishes Atherogenesis in Hyperlipidemic Mice

OBJECTIVE: MCPIP1 is a newly identified protein that profoundly impacts immunity and inflammation. We aim to test if MCPIP1 deficiency in hematopoietic cells results in systemic inflammation and accelerates atherogenesis in mice. APPROACH AND RESULTS: After lethally irradiated, LDLR(−/−) mice were t...

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Detalles Bibliográficos
Autores principales: Yu, Fang, Du, Fen, Wang, Yuzhen, Huang, Shengping, Miao, Ruidong, Major, Amy S., Murphy, E. Angela, Fu, Mingui, Fan, Daping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3819309/
https://www.ncbi.nlm.nih.gov/pubmed/24223214
http://dx.doi.org/10.1371/journal.pone.0080089

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3819309/
https://www.ncbi.nlm.nih.gov/pubmed/24223214
http://dx.doi.org/10.1371/journal.pone.0080089

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