An Over Expression APP Model for Anti-Alzheimer Disease Drug Screening Created by Zinc Finger Nuclease Technology

Zinc Finger Nucleases (ZFNs), famous for their ability to precisely and efficiently modify specific genomic loci, have been employed in numerous transgenic model organism and cell constructions. Here we employ the ZFNs technology, with homologous recombination (HR), to construct sequence-specific Am...

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Detalles Bibliográficos
Autores principales: Zhang, Xiaojing, Li, Hui, Mao, Yiqing, Li, Zhixin, Wang, Rong, Guo, Tingting, Jin, Ling, Song, Rongjing, Xu, Wei, Zhou, Na, Zhang, Yizhuang, Hu, Ruobi, Wang, Xi, Huang, Huakang, Lei, Zhen, Niu, Gang, Irwin, David M., Tan, Huanran
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3819351/
https://www.ncbi.nlm.nih.gov/pubmed/24223114
http://dx.doi.org/10.1371/journal.pone.0075493

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3819351/
https://www.ncbi.nlm.nih.gov/pubmed/24223114
http://dx.doi.org/10.1371/journal.pone.0075493

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