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Roles of the Linker Region of RNA Helicase A in HIV-1 RNA Metabolism

RNA helicase A (RHA) promotes multiple steps in HIV-1 production including transcription and translation of viral RNA, annealing of primer tRNA(Lys3) to viral RNA, and elevating the ratio of unspliced to spliced viral RNA. At its amino terminus are two double-stranded RNA binding domains (dsRBDs) th...

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Detalles Bibliográficos
Autores principales: Xing, Li, Niu, Meijuan, Zhao, Xia, Kleiman, Lawrence
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3819368/
https://www.ncbi.nlm.nih.gov/pubmed/24223160
http://dx.doi.org/10.1371/journal.pone.0078596