Fhit Delocalizes Annexin A4 from Plasma Membrane to Cytosol and Sensitizes Lung Cancer Cells to Paclitaxel

Fhit protein is lost or reduced in a large fraction of human tumors, and its restoration triggers apoptosis and suppresses tumor formation or progression in preclinical models. Here, we describe the identification of candidate Fhit-interacting proteins with cytosolic and plasma membrane localization...

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Detalles Bibliográficos
Autores principales: Gaudio, Eugenio, Paduano, Francesco, Spizzo, Riccardo, Ngankeu, Apollinaire, Zanesi, Nicola, Gaspari, Marco, Ortuso, Francesco, Lovat, Francesca, Rock, Jonathan, Hill, Grace A., Kaou, Mohamed, Cuda, Giovanni, Aqeilan, Rami I., Alcaro, Stefano, Croce, Carlo M., Trapasso, Francesco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3819369/
https://www.ncbi.nlm.nih.gov/pubmed/24223161
http://dx.doi.org/10.1371/journal.pone.0078610

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