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Synthesis and characterization of novel bioactive 1,2,4-oxadiazole natural product analogs bearing the N-phenylmaleimide and N-phenylsuccinimide moieties

Taking into consideration the biological activity of the only natural products containing a 1,2,4-oxadiazole ring in their structure (quisqualic acid and phidianidines A and B), the natural product analogs 1-(4-(3-tert-butyl-1,2,4-oxadiazol-5-yl)phenyl)pyrrolidine-2,5-dione (4) and 1-(4-(3-tert-buty...

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Detalles Bibliográficos
Autores principales: Maftei, Catalin V, Fodor, Elena, Jones, Peter G, Franz, M Heiko, Kelter, Gerhard, Fiebig, Heiner, Neda, Ion
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Beilstein-Institut 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3819603/
https://www.ncbi.nlm.nih.gov/pubmed/24222789
http://dx.doi.org/10.3762/bjoc.9.259