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Human endogenous retrovirus K (HML-2) RNA and protein expression is a marker for human embryonic and induced pluripotent stem cells

BACKGROUND: Malignant human embryonal carcinoma cells (ECCs) rely on similar transcriptional networks as non-malignant embryonic stem cells (ESCs) to control selfrenewal, maintain pluripotency, and inhibit differentiation. Because re-activation of silenced HERV-K(HML-2) loci is a hallmark of ECCs, w...

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Detalles Bibliográficos
Autores principales:	Fuchs, Nina V, Loewer, Sabine, Daley, George Q, Izsvák, Zsuzsanna, Löwer, Johannes, Löwer, Roswitha
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2013
Materias:	Short Report
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3819666/ https://www.ncbi.nlm.nih.gov/pubmed/24156636 http://dx.doi.org/10.1186/1742-4690-10-115

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