Increased pfmdr1 gene copy number and the decline in pfcrt and pfmdr1 resistance alleles in Ghanaian Plasmodium falciparum isolates after the change of anti-malarial drug treatment policy

BACKGROUND: With the introduction of artemisinin-based combination therapy (ACT) in 2005, monitoring of anti-malarial drug efficacy, which includes the use of molecular tools to detect known genetic markers of parasite resistance, is important for first-hand information on the changes in parasite su...

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Detalles Bibliográficos
Autores principales: Duah, Nancy O, Matrevi, Sena A, de Souza, Dziedzom K, Binnah, Daniel D, Tamakloe, Mary M, Opoku, Vera S, Onwona, Christiana O, Narh, Charles A, Quashie, Neils B, Abuaku, Benjamin, Duplessis, Christopher, Kronmann, Karl C, Koram, Kwadwo A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3819684/
https://www.ncbi.nlm.nih.gov/pubmed/24172030
http://dx.doi.org/10.1186/1475-2875-12-377

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