New aQTL SNPs for the CYP2D6 Identified by a Novel Mediation Analysis of Genome-Wide SNP Arrays, Gene Expression Arrays, and CYP2D6 Activity

Background. The genome-wide association studies (GWAS) have been successful during the last few years. A key challenge is that the interpretation of the results is not straightforward, especially for transacting SNPs. Integration of transcriptome data into GWAS may provide clues elucidating the mech...

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Detalles Bibliográficos
Autores principales: Jiang, Guanglong, Chakraborty, Arindom, Wang, Zhiping, Boustani, Malaz, Liu, Yunlong, Skaar, Todd, Li, Lang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3819829/
https://www.ncbi.nlm.nih.gov/pubmed/24232670
http://dx.doi.org/10.1155/2013/493019

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3819829/
https://www.ncbi.nlm.nih.gov/pubmed/24232670
http://dx.doi.org/10.1155/2013/493019

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