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The Blood Lactate Increase in High Intensity Exercise Is Depressed by Acanthopanax sieboldianus

This study investigates the anti-fatigue effects of Acanthopanax sieboldianus (A. sieboldianus) at various exercise intensities. Two experiments were conducted in 18 Sprague-Dawley rats. In Experiment 1, a three-stage increment test (15 m/min for 5 min, and 20 m/min for 5 min and 25 m/min for 10 min...

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Autores principales: Kato, Morimasa, Kurakane, Shizue, Nishina, Atsuyoshi, Park, Jaeyoung, Chang, Hyukki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3820064/
https://www.ncbi.nlm.nih.gov/pubmed/24135965
http://dx.doi.org/10.3390/nu5104134
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author Kato, Morimasa
Kurakane, Shizue
Nishina, Atsuyoshi
Park, Jaeyoung
Chang, Hyukki
author_facet Kato, Morimasa
Kurakane, Shizue
Nishina, Atsuyoshi
Park, Jaeyoung
Chang, Hyukki
author_sort Kato, Morimasa
collection PubMed
description This study investigates the anti-fatigue effects of Acanthopanax sieboldianus (A. sieboldianus) at various exercise intensities. Two experiments were conducted in 18 Sprague-Dawley rats. In Experiment 1, a three-stage increment test (15 m/min for 5 min, and 20 m/min for 5 min and 25 m/min for 10 min) was performed using a treadmill. In Experiment 2, a 10-min swimming test was conducted. Blood samples were extracted from each rat before, during and after the exercises and the blood concentrations of lactate and glucose measured. In both experiments, water (control) or A. sieboldianus solution (ASS) was administered orally using a zonde 30 min before the exercise. In the swimming test, ASS administration significantly decreased the blood lactate level measured at the end of the exercise and 5 min post-exercise relative to the water group, although the two groups did not differ significantly in the treadmill test. Our study demonstrates that a single oral administration of A. sieboldianus prior to high-intensity exercise significantly decreases the blood lactate concentration suggesting that A. sieboldianus has an intrinsic anti-fatigue effect.
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spelling pubmed-38200642013-11-09 The Blood Lactate Increase in High Intensity Exercise Is Depressed by Acanthopanax sieboldianus Kato, Morimasa Kurakane, Shizue Nishina, Atsuyoshi Park, Jaeyoung Chang, Hyukki Nutrients Article This study investigates the anti-fatigue effects of Acanthopanax sieboldianus (A. sieboldianus) at various exercise intensities. Two experiments were conducted in 18 Sprague-Dawley rats. In Experiment 1, a three-stage increment test (15 m/min for 5 min, and 20 m/min for 5 min and 25 m/min for 10 min) was performed using a treadmill. In Experiment 2, a 10-min swimming test was conducted. Blood samples were extracted from each rat before, during and after the exercises and the blood concentrations of lactate and glucose measured. In both experiments, water (control) or A. sieboldianus solution (ASS) was administered orally using a zonde 30 min before the exercise. In the swimming test, ASS administration significantly decreased the blood lactate level measured at the end of the exercise and 5 min post-exercise relative to the water group, although the two groups did not differ significantly in the treadmill test. Our study demonstrates that a single oral administration of A. sieboldianus prior to high-intensity exercise significantly decreases the blood lactate concentration suggesting that A. sieboldianus has an intrinsic anti-fatigue effect. MDPI 2013-10-16 /pmc/articles/PMC3820064/ /pubmed/24135965 http://dx.doi.org/10.3390/nu5104134 Text en © 2013 by the authors; licensee MDPI, Basel, Switzerland. http://creativecommons.org/licenses/by/3.0/ This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/3.0/).
spellingShingle Article
Kato, Morimasa
Kurakane, Shizue
Nishina, Atsuyoshi
Park, Jaeyoung
Chang, Hyukki
The Blood Lactate Increase in High Intensity Exercise Is Depressed by Acanthopanax sieboldianus
title The Blood Lactate Increase in High Intensity Exercise Is Depressed by Acanthopanax sieboldianus
title_full The Blood Lactate Increase in High Intensity Exercise Is Depressed by Acanthopanax sieboldianus
title_fullStr The Blood Lactate Increase in High Intensity Exercise Is Depressed by Acanthopanax sieboldianus
title_full_unstemmed The Blood Lactate Increase in High Intensity Exercise Is Depressed by Acanthopanax sieboldianus
title_short The Blood Lactate Increase in High Intensity Exercise Is Depressed by Acanthopanax sieboldianus
title_sort blood lactate increase in high intensity exercise is depressed by acanthopanax sieboldianus
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3820064/
https://www.ncbi.nlm.nih.gov/pubmed/24135965
http://dx.doi.org/10.3390/nu5104134
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