Val66Met Polymorphism of BDNF Alters Prodomain Structure to Induce Neuronal Growth Cone Retraction

A common single-nucleotide polymorphism in the human brain-derived neurotrophic factor (BDNF) gene results in a Val66Met substitution in the BDNF prodomain region. This single-nucleotide polymorphism is associated with alterations in memory and with enhanced risk to develop depression and anxiety di...

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Detalles Bibliográficos
Autores principales: Anastasia, Agustin, Deinhardt, Katrin, Chao, Moses V., Will, Nathan E., Irmady, Krithi, Lee, Francis S., Hempstead, Barbara L., Bracken, Clay
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3820160/
https://www.ncbi.nlm.nih.gov/pubmed/24048383
http://dx.doi.org/10.1038/ncomms3490

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