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Distribution of the Fittest Individuals and the Rate of Muller's Ratchet in a Model with Overlapping Generations
Muller's ratchet is a paradigmatic model for the accumulation of deleterious mutations in a population of finite size. A click of the ratchet occurs when all individuals with the least number of deleterious mutations are lost irreversibly due to a stochastic fluctuation. In spite of the simplic...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2013
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3820511/ https://www.ncbi.nlm.nih.gov/pubmed/24244123 http://dx.doi.org/10.1371/journal.pcbi.1003303 |