Prediction of Drug-Target Interactions for Drug Repositioning Only Based on Genomic Expression Similarity

Small drug molecules usually bind to multiple protein targets or even unintended off-targets. Such drug promiscuity has often led to unwanted or unexplained drug reactions, resulting in side effects or drug repositioning opportunities. So it is always an important issue in pharmacology to identify p...

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Detalles Bibliográficos
Autores principales: Wang, Kejian, Sun, Jiazhi, Zhou, Shufeng, Wan, Chunling, Qin, Shengying, Li, Can, He, Lin, Yang, Lun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3820513/
https://www.ncbi.nlm.nih.gov/pubmed/24244130
http://dx.doi.org/10.1371/journal.pcbi.1003315

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