Cargando…
The Role of Sulfhydryl Reactivity of Small Molecules for the Activation of the KEAP1/NRF2 Pathway and the Heat Shock Response
The KEAP1/NRF2 pathway and the heat shock response are two essential cytoprotective mechanisms that allow adaptation and survival under conditions of oxidative, electrophilic, and thermal stress by regulating the expression of elaborate networks of genes with versatile protective functions. The two...
Autor principal: | Dinkova-Kostova, Albena T. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2012
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3820647/ https://www.ncbi.nlm.nih.gov/pubmed/24278719 http://dx.doi.org/10.6064/2012/606104 |
Ejemplares similares
-
KEAP1 and done? Targeting the NRF2 pathway with sulforaphane
por: Dinkova-Kostova, Albena T., et al.
Publicado: (2017) -
Monitoring Keap1–Nrf2 interactions in single live cells
por: Baird, Liam, et al.
Publicado: (2014) -
The spatiotemporal regulation of the Keap1–Nrf2 pathway and its importance in cellular bioenergetics
por: Dinkova-Kostova, Albena T., et al.
Publicado: (2015) -
Loss of Nrf2 abrogates the protective effect of Keap1 downregulation in a preclinical model of cutaneous squamous cell carcinoma
por: Knatko, Elena V., et al.
Publicado: (2016) -
The emerging role of Nrf2 in mitochondrial function
por: Dinkova-Kostova, Albena T., et al.
Publicado: (2015)