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Cyclic Nucleotide Dependent Dephosphorylation of Regulator of G-Protein Signaling 18 in Human Platelets

Regulator of G-protein signaling 18 (RGS18) is a GTPase-activating protein that turns off Gq signaling in platelets. RGS18 is regulated by binding to the adaptor protein 14-3-3 via phosphorylated serine residues S49 and S218 on RGS18. In this study we confirm that thrombin, thromboxane A2, or ADP st...

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Detalles Bibliográficos
Autores principales:	Gegenbauer, Kristina, Nagy, Zoltan, Smolenski, Albert
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3820651/ https://www.ncbi.nlm.nih.gov/pubmed/24244663 http://dx.doi.org/10.1371/journal.pone.0080251

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