Inference of Structure Ensembles of Flexible Biomolecules from Sparse, Averaged Data

We present the theoretical foundations of a general principle to infer structure ensembles of flexible biomolecules from spatially and temporally averaged data obtained in biophysical experiments. The central idea is to compute the Kullback-Leibler optimal modification of a given prior distribution...

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Detalles Bibliográficos
Autores principales: Olsson, Simon, Frellsen, Jes, Boomsma, Wouter, Mardia, Kanti V., Hamelryck, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3820694/
https://www.ncbi.nlm.nih.gov/pubmed/24244505
http://dx.doi.org/10.1371/journal.pone.0079439

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3820694/
https://www.ncbi.nlm.nih.gov/pubmed/24244505
http://dx.doi.org/10.1371/journal.pone.0079439

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